Work Package 2:
NIHR HIC TDA Database
The NIHR HIC TDA database is a Research Ethics Committee approved secure research database, containing information, collated from hospital and NHSBT records. The focus is on transfusions that patients have received, their blood groups and the antibodies they have developed. Additional information is also collected, for example what health conditions the person has and what their other blood results are.
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The database will allow us to understand the risk that a patient develops antibodies for different mismatches of blood groups. We need to know this to work out the best way to match patients to donors. It will be more important to match a blood group the greater the risk that an incompatibility generates an antibody in the patient.
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Data for the database has been gathered through collaboration with the NIHR Health Informatics Collaborative (HIC), NHS Blood and Transplant and NHS Trusts. The database has its own separate theme within the HIC known as the Transfusion Dependent Anaemia (TDA) theme.
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The database will be a crucial component to the development of the matching algorithm.
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